Research Fellow

Marie Skłodowska-Curie Research Fellow (full-time)
​​​​​​​BIO-MICRO Project
Affiliation: Randox Laboratories, Clinical Immunoassay R&D, Crumlin, UK

Offer Description:

We are looking for a highly motivated and proactive researcher who is able to work both independently and collaboratively within an interdisciplinary team focussing on micronutritional therapy in patients undergoing rehabilitation for cardiac surgery. You have strong analytical and problem-solving skills, with the ability to integrate multidisciplinary data. You have excellent communication skills for disseminating research findings. You have a collaborative mindset, with experience in interdisciplinary teams (e.g., clinicians, bioinformaticians, analytical chemists). The position includes intersectoral secondments in Universitätsklinikum Würzburg for 12 months. The project should result in the successful completion of a PhD thesis.

What will you do

RF6:
Development and validation of POC measurements of inflammation for inflammatory subphenotyping of cardiac surgery patients

• Duration: 36 months

Supervisor(s): Cecilia Fortugno, Kenneth Martin, Christian Stoppe University Hospital Würzburg (Universitätsklinikum Würzburg, UKW, www.ukw.de),
Tilman Grune German Institute of Human Nutrition, University of
Potsdam (DEUTSCHES INSTITUT FUER ERNAEHRUNGSFORSCHUNG POTSDAMREHBRUECKE),
Enrolment in a Doctoral Program: Universitätsklinikum Würzburg

Project description:

This PhD project will focus on identifying inflammation related biomarker combinations and data driven algorithms to classify cardiac surgery patient subphenotypes. Using advanced multiplex biomarker technologies, the project will support development of novel diagnostic tools to improve patient stratification and guide targeted micronutrient (MN) interventions. Randox has access to a broad and diverse biomarker multiplexing portfolio, including several novel biomarkers highly relevant to cardiac surgery and peri operative inflammation. The objectives will be:

• To develop multiplex inflammation biomarker POC measurements to subphenotype cardiac surgery patients
• To clinically validate and appropriately register the multiplex biochip product
• To identify cardiac surgery patient groups that would benefit from MN therapy intervention
• Commercialisation of products

To be eligible for this position, applicants must meet the Marie Skłodowska-Curie admission requirements:

• You must not already hold a doctoral degree.
• You must comply with the MSCA mobility rule: you must not have resided in or carried out your main activity (work, studies, etc.) in the UK for more than 12 months during the three years immediately prior to recruitment.
• In addition, you meet the following requirements and experience:

Essential criteria

• A Master’s degree in a relevant discipline such as biomedical science, biochemistry, immunology, molecular biology, bioengineering, data science, or a related field
• Strong interest in biomarker discovery, inflammation biology, and clinical research
• Experience or aptitude for quantitative data analysis and interpretation
• Ability to work independently while contributing effectively within multidisciplinary academic and industrial teams
• Excellent written and verbal communication skills in English